Research Opportunities

This page connects researchers and participants for current, and ongoing research. For findings from recently completed research, please visit Research Findings .

We have listed a few of the current studies and trials specific to pediatric stroke, but encourage families to use the information under Clinical Trials to search for other opportunities that may be in your area.

As a researcher, if you would like us to include your study on the Currently Recruiting list, please contact us! We would be happy to help with recruitment.

Research Studies and Trials Currently Recruiting

I-ACQUIRE Clinical Trial
The recruitment phase of I-AQUIRE Clinical Trial for infants and toddlers (8 months to 24 months old) who have had a stroke has now started. This intensive therapy is at no additional cost (excluding travel/housing arrangements) and will be provided in 12 different locations across the U.S. For more information, including who to contact see the I-ACQUIRE two page flyer. Page 1 and Page 2

This is a Phase III multi-site randomized controlled trial comparing 2 dosages of a form of intensive pediatric rehabilitation known as Infant ACQUIRE (I-ACQUIRE) to Usual and Customary treatment (U&CT).

The Fralin Biomedical Research Institute, a university-level research institute of Virginia Tech, will oversee the I-ACQUIRE Phase III trial, which includes funding for the program leadership’s work in Roanoke as well as sub-awards to a national coordinating center at the University of Cincinnati, a national assessment core at Ohio State University, statistics and data management center at the Medical University of South Carolina, and a neuroimaging center at Stanford University. Other clinical sites are: Ann Arbor, Michigan; Atlanta, Georgia; Baltimore, Maryland; Boston, Massachusetts; Chicago, Illinois; Cincinnati, Ohio; Columbus, Ohio; Houston, Texas; New Haven, Connecticut; Philadelphia, Pennsylvania; Roanoke, Virginia; and San Diego, California.

More information can be found on

Baby Brain Recovery Study
This study aims to assess, over the first two years of life, concurrent recovery and development of the infant brain and resultant function after perinatal stroke. They are recruiting families with 0-6 months old infants with a history of early brain injury. The visits will take place at the University of Wisconsin–Madison,Waisman Center, 1500 Highland Avenue in Madison, Wisconsin. There will be 8-9 study sessions (3-4 hours each) over 2 years. If you’re interested in participating or have questions, call 608-381-2699 or email Please see the Baby Brain Recovery Study brochure or visit (NCT number): NCT05013736 for more information.

Pediatric Brain and Movement Study
This study aims to assess the feasibility and ease of remote neuromodulation therapy with the goal to improve motor rehabilitation outcomes, reduce treatment cost, and improve access to health care. They are recruiting children between 8-17 years of age that have hemiparetic cerebral palsy. The study will be held in the home setting with visits by a study team member. They offer weekday, evening, and weekend study visits to accommodate family schedules. If you are interested in participating or have questions, call 608-381-2699, or email More information can be found on the website, study brochure, or on

Research Studies on Recovery after Perinatal and Childhood Stroke, Washington, DC, area
Researchers at the Center for Brain Plasticity and Recovery (CBPR) at Georgetown University Medical Center in Washington, DC, are studying the effects of childhood stroke on cognitive and language abilities.

You and your child can help with this important research that involves absolutely zero radiation or needles! They are looking for children, teens, and young adults age 11 and older who had a stroke around the time of birth or during childhood. Siblings, friends, and adult survivors of pediatric stroke are also welcome! They are happy to help arrange transportation to and from Georgetown University Medical Center. Participants will be paid for their time and, if from out of town, provided with hotel and transportation to and from Washington, DC.

If you are willing to participate, please email or call 202-687-3727. To find out more about research studies at the Center for Brain Plasticity and Recovery, please visit their website. A full description can be found here.

Research Studies on Pediatric Hemiplegia in Chicago, IL
Do you have a child with weakness in one arm from childhood-onset hemiplegia? If so, your child is invited to participate in a pediatric hemiplegia study at Northwestern University. Participants will be compensated. To learn more about the research study, click here.
Contact Heidi Roth at or 312-503-6018 if you are interested!

Clinical Trials is a database of privately and publicly funded clinical studies conducted around the world. You can search by condition or disease (i.e. “pediatric stroke”, “hemiplegia”, “perinatal stroke”),  location, recruiting, completed, or terminated. The listings are updated regularly, so you are encouraged to check the site frequently.

We’ve made it easier for you by providing direct links to some of the terms associated with pediatric stroke. for Pediatric Stroke, recruiting/not yet recruiting for Perinatal Stroke, recruiting/not yet recruiting for Hemiplegia, (birth to 17 years) recruiting/not yet recruiting for Cerebral Palsy, (birth to 17 years) recruiting/not yet recruiting

International Pediatric Stroke Study

The International Pediatric Stroke Study (IPSS) performs collaborative research aimed at understanding, preventing and improving outcomes in pediatric stroke, and to promote professional education, support families with pediatric stroke members, and support public education.

The IPSS currently includes over 150 participating research staff, investigators and collaborators from 55 active centers that have enrolled over 5600 children with stroke. Establishing this network has led to successful competitions for millions of dollars in research grants to fund the execution of the multicentre research studies and clinical trials required to advance knowledge and improve outcomes.

Please see the International Pediatric Stroke Study Colleagues and Collaborators list, to locate centers who participate in the IPSS worldwide. If you would like to contact IPSS directly, please send an email to

Patient-Centered Outcomes Research Institute (PCORI)

The Patient-Centered Outcomes Research Institute was established to fund research that can help patients and those who care for them make better-informed decisions about the healthcare choices they face every day, guided by those who will use that information. As the largest public research funder that focuses primarily on Clinical Effectiveness Research (CER), they issue funding announcements several times each year that call for proposals for CER projects. They include patients and other healthcare stakeholders throughout the research process, so the resulting evidence will address their most important questions and concerns.

PCORI sends weekly emails to notify you of newly funded research and engagement awards, opportunities to apply for funding, results of our funded research, stakeholder workshops, and original featured stories about their work.